BDBM50178221 CHEMBL3814602
SMILES C[C@@H]1CC(=O)Nc2cccc(-c3ccc4n(C)nc(C#N)c4c3)c2N1
InChI Key InChIKey=BVGBDKUISALXAL-LLVKDONJSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50178221
Affinity DataEC50: 7.00E+3nMAssay Description:Inhibition of Halo-tagged histone H3.3 binding to CBP (unknown origin) expressed in HEK293 cells after overnight incubation by luciferase reporter ge...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Displacement of biotinylated ligand from recombinant His-tagged CBP (unknown origin) incubated for 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Constellation Pharmaceuticals
Curated by ChEMBL
Constellation Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Displacement of biotinylated ligand from recombinant His-tagged BRD4 bromodomain-1 (unknown origin) incubated for 10 mins by TR-FRET assayMore data for this Ligand-Target Pair