BDBM50178273 CHEMBL202775::N-((2-(2-cyclopropoxy-5-(trifluoromethoxy)benzylamino)-1-(4-fluorophenyl)-8-aza-bicyclo[3.2.1]octan-6-yl)methyl)benzenesulfonamide

SMILES Fc1ccc(cc1)C12CC(CNS(=O)(=O)c3ccccc3)C(CCC1NCc1cc(OC(F)(F)F)ccc1OC1CC1)N2

InChI Key InChIKey=KKKGFVLMGTXNNX-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50178273   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178273(CHEMBL202775 | N-((2-(2-cyclopropoxy-5-(trifluorom...)
Affinity DataKi:  190nMAssay Description:Displacement of [35S]-labelled MK499 from cloned hERG potassium channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178273(CHEMBL202775 | N-((2-(2-cyclopropoxy-5-(trifluorom...)
Affinity DataIC50:  0.240nMAssay Description:Displacement of [125I]-labelled substance P from cloned human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed