BDBM50178276 5-(2-(2-cyclopropoxy-5-(trifluoromethoxy)benzylamino)-1-phenyl-8-aza-bicyclo[3.2.1]octan-6-yl)-2H-1,2,4-triazol-3(4H)-one::CHEMBL379010

SMILES FC(F)(F)Oc1ccc(OC2CC2)c(CNC2CCC3NC2(CC3c2n[nH]c(=O)[nH]2)c2ccccc2)c1

InChI Key InChIKey=QKMNCMIKEOYLQG-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50178276   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178276(5-(2-(2-cyclopropoxy-5-(trifluoromethoxy)benzylami...)
Affinity DataKi:  5.80E+3nMAssay Description:Displacement of [35S]-labelled MK499 from cloned hERG potassium channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178276(5-(2-(2-cyclopropoxy-5-(trifluoromethoxy)benzylami...)
Affinity DataIC50:  0.610nMAssay Description:Displacement of [125I]-labelled substance P from cloned human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed