BDBM50178526 5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazol-5-yl)-N-(4-(trifluoromethyl)phenyl)-1,3,4-oxadiazol-2-amine::CHEMBL380131

SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(cc2)C(F)(F)F)o1

InChI Key InChIKey=OJYUHOMVZDAJEB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50178526   

TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50178526(5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazo...)
Affinity DataIC50:  120nMAssay Description:Inhibition of VEGFR1 by enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50178526(5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazo...)
Affinity DataIC50:  82nMAssay Description:Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50178526(5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazo...)
Affinity DataIC50:  73nMAssay Description:Inhibition of VEGFR2 by enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed