BDBM50178757 3-(Dmt-Tic-NH-butyl)-6-(Dmt-Tic-NH-propyl)-2-(1H)-pyrazinone::CHEMBL370398

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCCCCc1nc(C)c(CCCNC(=O)C2Cc3ccccc3CN2C(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)[nH]c1=O

InChI Key InChIKey=CHKFIUAMEUVMNR-FHRQCFKPSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50178757   

TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50178757(3-(Dmt-Tic-NH-butyl)-6-(Dmt-Tic-NH-propyl)-2-(1H)-...)
Affinity DataKi:  0.0920nMAssay Description:Displacement of [3H]deltorphin-II from delta opioid receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50178757(3-(Dmt-Tic-NH-butyl)-6-(Dmt-Tic-NH-propyl)-2-(1H)-...)
Affinity DataKi:  2.28nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50178757(3-(Dmt-Tic-NH-butyl)-6-(Dmt-Tic-NH-propyl)-2-(1H)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Agonistic activity at mu opioid receptor in myenteric plexus longitudinal muscle of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50178757(3-(Dmt-Tic-NH-butyl)-6-(Dmt-Tic-NH-propyl)-2-(1H)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Agonistic activity at delta opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed