BDBM50178832 CHEMBL203535::N-(2'-(phenylamino)-4,4'-bipyridin-2-yl)tetrahydrofuran-3-carboxamide::N-(4-(2-(phenylamino)pyridin-4-yl)pyridin-2-yl)-tetrahydrofuran-3-carboxamide
SMILES O=C(Nc1cc(ccn1)-c1ccnc(Nc2ccccc2)c1)C1CCOC1
InChI Key InChIKey=YZIQMIAREGGHFQ-UHFFFAOYSA-N
Data 13 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50178832
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje
Curated by ChEMBL
Astrazeneca R&D SöDertäLje
Curated by ChEMBL
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje
Curated by ChEMBL
Astrazeneca R&D SöDertäLje
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje
Curated by ChEMBL
Astrazeneca R&D SöDertäLje
Curated by ChEMBL
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje
Curated by ChEMBL
Astrazeneca R&D SöDertäLje
Curated by ChEMBL
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje
Curated by ChEMBL
Astrazeneca R&D SöDertäLje
Curated by ChEMBL
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje
Curated by ChEMBL
Astrazeneca R&D SöDertäLje
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje
Curated by ChEMBL
Astrazeneca R&D SöDertäLje
Curated by ChEMBL
Affinity DataIC50: 6.31nMAssay Description:Inhibition of JNK3 by high throughput screeningMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje
Curated by ChEMBL
Astrazeneca R&D SöDertäLje
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of p38alpha by high throughput screeningMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 5-kinase type-1 alpha(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PIP5Kalpha (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 5-kinase type-1 beta(Homo sapiens)
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PIP5Kbeta (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 5-kinase type-1 gamma(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 670nMAssay Description:Inhibition of PIP5Kgamma (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje
Curated by ChEMBL
Astrazeneca R&D SöDertäLje
Curated by ChEMBL
Affinity DataIC50: 398nMAssay Description:Inhibition of JNK1 by high throughput screeningMore data for this Ligand-Target Pair