BDBM50178839 CHEMBL202676::cis-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyridin-2-yl)-4-methoxycyclohexanecarboxamide

SMILES CO[C@H]1CC[C@H](CC1)C(=O)Nc1cc(ccn1)-c1ccnc(Nc2ccc(F)cc2)c1

InChI Key InChIKey=ACGBFWCBVIXTPZ-NBEIKUQISA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50178839   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178839(CHEMBL202676 | cis-N-(4-(2-(4-fluorophenylamino)py...)
Affinity DataIC50:  40nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178839(CHEMBL202676 | cis-N-(4-(2-(4-fluorophenylamino)py...)
Affinity DataIC50:  15nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178839(CHEMBL202676 | cis-N-(4-(2-(4-fluorophenylamino)py...)
Affinity DataIC50:  88nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair