BDBM50178916 9-cyclopropyl-6-fluoro-7-(4-(hydroxymethyl)phenyl)isothiazolo[5,4-b]quinoline-3,4(2H,9H)-dione::CHEMBL203002

SMILES OCc1ccc(cc1)-c1cc2n(C3CC3)c3s[nH]c(=O)c3c(=O)c2cc1F

InChI Key InChIKey=YCVBALOHZCSOAU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50178916   

TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178916(9-cyclopropyl-6-fluoro-7-(4-(hydroxymethyl)phenyl)...)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibitory activity against wild type Staphylococcus aureus topoisomerase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178916(9-cyclopropyl-6-fluoro-7-(4-(hydroxymethyl)phenyl)...)
Affinity DataIC50:  900nMAssay Description:Inhibitory activity against wild type Escherichia coli gyraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed