BDBM50179114 (2E,4E)-6-((3,5-di-tert-butylphenyl)(propyl)amino)-3-methylhexa-2,4-dienoic acid::CHEMBL379057

SMILES CCCN(C\C=C\C(\C)=C\C(O)=O)c1cc(cc(c1)C(C)(C)C)C(C)(C)C

InChI Key InChIKey=NJUNLFLTZKMXMQ-NJESZQPCSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50179114   

TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179114((2E,4E)-6-((3,5-di-tert-butylphenyl)(propyl)amino)...)
Affinity DataKi:  17nMAssay Description:Binding affinity to RXRalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179114((2E,4E)-6-((3,5-di-tert-butylphenyl)(propyl)amino)...)
Affinity DataKi:  34nMAssay Description:Binding affinity to RXRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-gamma(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179114((2E,4E)-6-((3,5-di-tert-butylphenyl)(propyl)amino)...)
Affinity DataKi:  38nMAssay Description:Binding affinity to RXRgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179114((2E,4E)-6-((3,5-di-tert-butylphenyl)(propyl)amino)...)
Affinity DataEC50:  69nMAssay Description:Transactivation of RXRbeta in CV1 cells by cotransfection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179114((2E,4E)-6-((3,5-di-tert-butylphenyl)(propyl)amino)...)
Affinity DataEC50:  99nMAssay Description:Transactivation of RXRalpha in CV1 cells by cotransfection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-gamma(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179114((2E,4E)-6-((3,5-di-tert-butylphenyl)(propyl)amino)...)
Affinity DataEC50:  63nMAssay Description:Transactivation of RXRgamma in CV1 cells by cotransfection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed