BDBM50179866 CHEMBL380851::N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-isobutylthiophene-2-sulfonamide

SMILES CC(C)CN(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1cccs1

InChI Key InChIKey=WCUSZTFTCOTZHT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50179866   

TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50179866(CHEMBL380851 | N-(4-(1,1,1,3,3,3-hexafluoro-2-hydr...)
Affinity DataEC50:  40nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed