BDBM50179996 4,2'-difluoro-5'-(7-trifluoromethyl-imidazo[1,2-a]pyrimidin-3-yl)-biphenyl-2-carbonitrile::4,2-difluoro-5-(7-trifluoromethylimidazo[1,2-a]pyrimidin-3-yl)biphenyl-2-carbonitrile::CHEMBL369902
SMILES Fc1ccc(c(c1)C#N)-c1cc(ccc1F)-c1cnc2nc(ccn12)C(F)(F)F
InChI Key InChIKey=XXRKXVKJMSIZSM-UHFFFAOYSA-N
Data 6 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50179996
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp Laboratory
Curated by ChEMBL
Merck Sharp Laboratory
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]Ro-151788 from human recombinant GABAA alpha5 in combination with beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.730nMAssay Description:Displacement of [3H] Ro15-1788 from recombinant human GABAA alpha2 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp Laboratory
Curated by ChEMBL
Merck Sharp Laboratory
Curated by ChEMBL
Affinity DataKi: 0.730nMAssay Description:Displacement of [3H]Ro-151788 from human recombinant GABAA alpha3 in combination with beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]-Ro15-1788 from human recombinant GABAA alpha2 in combination with beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]Ro 15-1788 from recombinant human GABAA alpha1 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]-Ro15-1788 from human recombinant GABAA alpha1 in combination with beta-3-gamma-2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair