BDBM50180358 2-[3-(2-Aminoethoxy)phenylamino]-6-(3-acetamidophenyl)-pyrazine::CHEMBL199355

SMILES CC(=O)Nc1cccc(c1)-c1cncc(Nc2cccc(OCCN)c2)n1

InChI Key InChIKey=ZKFXUGYLQAMRAD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50180358   

TargetSerine/threonine-protein kinase B-raf(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50180358(2-[3-(2-Aminoethoxy)phenylamino]-6-(3-acetamidophe...)
Affinity DataIC50:  5.20E+3nMAssay Description:Growth inhibition in human melanoma cells WM266.4 expressing mutant B-RAF with SRBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50180358(2-[3-(2-Aminoethoxy)phenylamino]-6-(3-acetamidophe...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibitory activity against human B-RAFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed