BDBM50180560 4-(4-bromo-2-fluorophenylamino)-5-chloro-N-(2-hydroxyethoxy)-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxamide::CHEMBL199774

SMILES Cn1cc(C(=O)NOCCO)c(Nc2ccc(Br)cc2F)c(Cl)c1=O

InChI Key InChIKey=JPNCXXZQRZRCKS-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50180560   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Array Biopharma

Curated by ChEMBL

LigandBDBM50180560(4-(4-bromo-2-fluorophenylamino)-5-chloro-N-(2-hydr...)Copy SMILESCopy InChI

Affinity DataIC50:  45nMAssay Description:Inhibitory activity aginst MEK1More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
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