BDBM50180570 4-(4-bromo-2-fluorophenylamino)-5-fluoro-N-methoxy-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxamide::CHEMBL201156

SMILES CONC(=O)c1cn(C)c(=O)c(F)c1Nc1ccc(Br)cc1F

InChI Key InChIKey=AROVPXKNYNWWMA-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50180570   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Array Biopharma

Curated by ChEMBL

LigandBDBM50180570(4-(4-bromo-2-fluorophenylamino)-5-fluoro-N-methoxy...)Copy SMILESCopy InChI

Affinity DataIC50:  43nMAssay Description:Inhibitory activity aginst MEK1More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL