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BDBM50180695 CHEMBL3819080

SMILES: Cc1c(ccc(C#N)c1C(F)(F)F)C(O)(c1ccco1)C(F)(F)F

InChI Key: InChIKey=BBMHFIQLGKNLOC-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50180695   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Androgen Receptor


(Homo sapiens (human))
BDBM50180695
PNG
(CHEMBL3819080)
Show SMILES Cc1c(ccc(C#N)c1C(F)(F)F)C(O)(c1ccco1)C(F)(F)F
Show InChI InChI=1S/C15H9F6NO2/c1-8-10(5-4-9(7-22)12(8)14(16,17)18)13(23,15(19,20)21)11-3-2-6-24-11/h2-6,23H,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 0.251n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Modulation of human androgen receptor expressed in African green monkey CV1 cells after 24 hrs by luciferase reporter gene assay


ACS Med Chem Lett 7: 83-8 (2016)


Article DOI: 10.1021/acsmedchemlett.5b00377
BindingDB Entry DOI: 10.7270/Q2K35WMN
More data for this
Ligand-Target Pair