BDBM50180746 8-(pyridin-2-yl)-7H-purine::8-pyridin-2-yl-7(9)H-purine::CHEMBL371544

SMILES c1ccc(nc1)-c1nc2ncncc2[nH]1

InChI Key InChIKey=IKLBKJSFSNHGKO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50180746   

TargetMethionine aminopeptidase(Escherichia coli (strain K12))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50180746(8-(pyridin-2-yl)-7H-purine | 8-pyridin-2-yl-7(9)H-...)
Affinity DataIC50:  376nMAssay Description:Inhibition of Co2+ loaded MetAP expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM50180746(8-(pyridin-2-yl)-7H-purine | 8-pyridin-2-yl-7(9)H-...)
Affinity DataIC50:  3.64E+4nMAssay Description:Inhibition of human MetAP2 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM50180746(8-(pyridin-2-yl)-7H-purine | 8-pyridin-2-yl-7(9)H-...)
Affinity DataIC50:  3.39E+4nMAssay Description:Inhibition of human MetAP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed