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BDBM50180950 CHEMBL3818203

SMILES: ONC(=O)CC[C@H](Cc1ccc(cc1)C(O)=O)C(O)=O

InChI Key: InChIKey=VUDGMYIWOPKVSL-SNVBAGLBSA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50180950   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate carboxypeptidase II


(Homo sapiens (Human))
BDBM50180950
PNG
(CHEMBL3818203)
Show SMILES ONC(=O)CC[C@H](Cc1ccc(cc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C13H15NO6/c15-11(14-20)6-5-10(13(18)19)7-8-1-3-9(4-2-8)12(16)17/h1-4,10,20H,5-7H2,(H,14,15)(H,16,17)(H,18,19)/t10-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
PDB
UniChem

Similars

PDB
Article
PubMed
n/an/a 44n/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of human recombinant GCP2 expressed in Schneider 2 cells preincubated for 15 mins using [3H]-NAAG/NAAG as substrate measured after 20 mins...


J Med Chem 59: 4539-50 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01806
BindingDB Entry DOI: 10.7270/Q2154JZB
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)