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BDBM50181730 (Z)-5-(4'-Chlorobenzylidene)-2-thioxothiazolidin-4-one::(Z)-5-(4-Chlorobenzylidene)-2-thioxothiazolidin-4-one::(Z)-5-(4-chlorobenzyliden)-2-thioxothiazolidin-4-one::5-(4-chlorobenzylidene)-2-thioxothiazolidin-4-one::5-(4-chlorobenzylidene)-4-oxo-2-thionothiazolidine::CHEMBL201467

SMILES: SC1=NC(=O)C(S1)=Cc1ccc(Cl)cc1

InChI Key: InChIKey=HIWUQEXWRIIIKB-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50181730   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arylamine N-acetyltransferase 1


(Homo sapiens)
BDBM50181730
PNG
((Z)-5-(4'-Chlorobenzylidene)-2-thioxothiazolidin-4...)
Show SMILES SC1=NC(=O)C(S1)=Cc1ccc(Cl)cc1
Show InChI InChI=1S/C10H6ClNOS2/c11-7-3-1-6(2-4-7)5-8-9(13)12-10(14)15-8/h1-5H,(H,12,13,14)
PDB
MMDB

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Article
PubMed
n/an/a 4.70E+3n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of human recombinant NAT1 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's method


Bioorg Med Chem 17: 905-18 (2009)


Article DOI: 10.1016/j.bmc.2008.11.032
BindingDB Entry DOI: 10.7270/Q2PZ58Q3
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50181730
PNG
((Z)-5-(4'-Chlorobenzylidene)-2-thioxothiazolidin-4...)
Show SMILES SC1=NC(=O)C(S1)=Cc1ccc(Cl)cc1
Show InChI InChI=1S/C10H6ClNOS2/c11-7-3-1-6(2-4-7)5-8-9(13)12-10(14)15-8/h1-5H,(H,12,13,14)
UniProtKB/TrEMBL

B.MOAD
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Patents


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Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV delta 21 NS5b RNA polymerase


J Med Chem 49: 1034-46 (2006)


Article DOI: 10.1021/jm050859x
BindingDB Entry DOI: 10.7270/Q2CJ8D3W
More data for this
Ligand-Target Pair