BDBM50182349 5-(methylsulfonyl)-2-(5-(4-(thiazol-5-yl)phenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)pyridine::CHEMBL205938

SMILES CS(=O)(=O)c1ccc(nc1)-n1nc(cc1-c1ccc(cc1)-c1cncs1)C(F)(F)F

InChI Key InChIKey=PRRPLFRTAPIUJF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182349   

TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182349(5-(methylsulfonyl)-2-(5-(4-(thiazol-5-yl)phenyl)-3...)
Affinity DataIC50:  180nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50182349(5-(methylsulfonyl)-2-(5-(4-(thiazol-5-yl)phenyl)-3...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed