BDBM50182494 CHEMBL3817891::US9512121, 13

SMILES CN1C(=O)COc2c1cnc1ccc(Sc3nnc4c(OC(F)F)cc(cn34)-c3cnn(C)c3)cc21

InChI Key InChIKey=WZOQEUJUJMLGMW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182494   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50182494(CHEMBL3817891 | US9512121, 13)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of c-Met (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50182494(CHEMBL3817891 | US9512121, 13)
Affinity DataIC50: >1.00E+3nMT: 2°CAssay Description:Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...More data for this Ligand-Target Pair
In DepthDetails US Patent