BDBM50183344 CHEMBL3818101

SMILES COc1cccc(OC)c1-c1cc(nn1-c1ccc(F)cc1)C(=O)N[C@@H](CC(C)C)CC(O)=O

InChI Key InChIKey=TUNZYSMSTFSVDK-KRWDZBQOSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50183344   

TargetApelin receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50183344(CHEMBL3818101)
Affinity DataKi:  600nMAssay Description:Displacement of [125I]-apelin13 from human APJ receptor expressed in CHOK1 cell membranes after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApelin receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50183344(CHEMBL3818101)
Affinity DataEC50:  9.40E+3nMAssay Description:Agonist activity at human APJ receptor expressed in cells c-expressing Galphaq16 assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed