BDBM50183757 (2S,3S)-dibenzyl 1-((S)-1-((R)-2-(tert-butoxycarbonyl)-4-methylpentanoyl)pyrrolidine-5-carbonyl)aziridine-2,3-dicarboxylate::CHEMBL382388

SMILES CC(C)C[C@@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)N1[C@@H]([C@H]1C(=O)OCc1ccccc1)C(=O)OCc1ccccc1

InChI Key InChIKey=XFYWHOCFLQPKMK-UNFRKHOWSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50183757   

TargetCruzipain(Trypanosoma cruzi)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50183757((2S,3S)-dibenzyl 1-((S)-1-((R)-2-(tert-butoxycarbo...)
Affinity DataKi:  790nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183757((2S,3S)-dibenzyl 1-((S)-1-((R)-2-(tert-butoxycarbo...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183757((2S,3S)-dibenzyl 1-((S)-1-((R)-2-(tert-butoxycarbo...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50183757((2S,3S)-dibenzyl 1-((S)-1-((R)-2-(tert-butoxycarbo...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of human cathepsin-L using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50183757((2S,3S)-dibenzyl 1-((S)-1-((R)-2-(tert-butoxycarbo...)
Affinity DataKi:  2.83E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 using Z-Phe-Arg-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed