BDBM50183802 CHEMBL379768::N-(4-(methylsulfonyl)phenyl)-N-(1-(3-(6-(2-(methylsulfonyl)propan-2-yl)quinolin-8-yl)phenyl)ethyl)cyclopropanecarboxamide
SMILES CC(N(C(=O)C1CC1)c1ccc(cc1)S(C)(=O)=O)c1cccc(c1)-c1cc(cc2cccnc12)C(C)(C)S(C)(=O)=O
InChI Key InChIKey=BVJRFNKHFQRJTE-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50183802
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Ability to block TNFalpha release through inhibition of PDE4 in LPS-stimulated human whole bloodMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human GST-PDE4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human GST-PDE4CMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human GST-PDE4AMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human GST-PDE4DMore data for this Ligand-Target Pair