BDBM50184248 2-(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)-1H-indazol-5-yl)acetic acid::CHEMBL210917

SMILES CCCc1c(OCCCn2ncc3cc(CC(O)=O)ccc23)ccc2c(noc12)C(F)(F)F

InChI Key InChIKey=ZFCIXIWMXLHUDY-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50184248   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184248(2-(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...)
Affinity DataEC50:  580nMAssay Description:Activity at LXR beta as beta-lactamase transactivation in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184248(2-(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...)
Affinity DataIC50:  87nMAssay Description:Inhibition of LXR betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184248(2-(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...)
Affinity DataIC50:  24nMAssay Description:Inhibition of PPAR deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184248(2-(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...)
Affinity DataIC50:  780nMAssay Description:Inhibition of PPAR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184248(2-(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...)
Affinity DataEC50:  480nMAssay Description:Activity at LXR alpha as beta-lactamase transactivation in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184248(2-(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...)
Affinity DataIC50:  73nMAssay Description:Inhibition of LXR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed