BDBM50184258 2-(3-methyl-4-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)phenyl)acetic acid::CHEMBL209563

SMILES CCCc1c(OCCCN(C)c2ccc(CC(O)=O)cc2C)ccc2c(noc12)C(F)(F)F

InChI Key InChIKey=GZAPSISRDWGGFB-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50184258   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184258(2-(3-methyl-4-(methyl(3-(7-propyl-3-(trifluorometh...)
Affinity DataIC50:  320nMAssay Description:Inhibition of LXR betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184258(2-(3-methyl-4-(methyl(3-(7-propyl-3-(trifluorometh...)
Affinity DataIC50:  600nMAssay Description:Inhibition of PPAR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184258(2-(3-methyl-4-(methyl(3-(7-propyl-3-(trifluorometh...)
Affinity DataIC50:  39nMAssay Description:Inhibition of PPAR deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184258(2-(3-methyl-4-(methyl(3-(7-propyl-3-(trifluorometh...)
Affinity DataIC50:  580nMAssay Description:Activity at LXR alpha as beta-lactamase transactivation in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184258(2-(3-methyl-4-(methyl(3-(7-propyl-3-(trifluorometh...)
Affinity DataIC50:  460nMAssay Description:Inhibition of PPAR gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184258(2-(3-methyl-4-(methyl(3-(7-propyl-3-(trifluorometh...)
Affinity DataIC50:  460nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184258(2-(3-methyl-4-(methyl(3-(7-propyl-3-(trifluorometh...)
Affinity DataIC50:  600nMAssay Description:Agonist activity at PPARalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184258(2-(3-methyl-4-(methyl(3-(7-propyl-3-(trifluorometh...)
Affinity DataIC50:  39.0nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184258(2-(3-methyl-4-(methyl(3-(7-propyl-3-(trifluorometh...)
Affinity DataIC50:  460nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184258(2-(3-methyl-4-(methyl(3-(7-propyl-3-(trifluorometh...)
Affinity DataIC50:  39nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184258(2-(3-methyl-4-(methyl(3-(7-propyl-3-(trifluorometh...)
Affinity DataIC50:  600nMAssay Description:Agonist activity at PPARalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed