BDBM50184268 1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)-1H-indole-5-carboxylic acid::CHEMBL377218

SMILES CCCc1c(OCCCn2ccc3cc(ccc23)C(O)=O)ccc2c(noc12)C(F)(F)F

InChI Key InChIKey=WJPMVXGXXLNBEN-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50184268   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184268(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol...)
Affinity DataIC50:  199nMAssay Description:Inhibition of LXR betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184268(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol...)
Affinity DataEC50:  2.80E+3nMAssay Description:Activity at LXR beta as beta-lactamase transactivation in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184268(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol...)
Affinity DataIC50:  72nMAssay Description:Activity at LXR alpha as beta-lactamase transactivation in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184268(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol...)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of PPAR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184268(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol...)
Affinity DataEC50:  1.90E+3nMAssay Description:Activity at LXR alpha as beta-lactamase transactivation in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed