BDBM50184270 2-(2-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)pyrimidin-5-yl)acetic acid::CHEMBL210990

SMILES CCCc1c(OCCCN(C)c2ncc(CC(O)=O)cn2)ccc2c(noc12)C(F)(F)F

InChI Key InChIKey=HNBMEVGNLQVKHO-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50184270   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184270(2-(2-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[...)
Affinity DataIC50:  55nMAssay Description:Inhibition of LXR betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184270(2-(2-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[...)
Affinity DataEC50:  620nMAssay Description:Activity at LXR alpha as beta-lactamase transactivation in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184270(2-(2-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[...)
Affinity DataIC50:  26nMAssay Description:Inhibition of LXR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184270(2-(2-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[...)
Affinity DataEC50:  470nMAssay Description:Activity at LXR beta as beta-lactamase transactivation in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed