BDBM50184495 1-methyl-5-[2-(6-methyl-pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-1H-indole::CHEMBL377717

SMILES Cc1cccc(n1)-c1nn2CCCc2c1-c1ccc2n(C)ccc2c1

InChI Key InChIKey=UHSVQDWWSUMJRF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50184495   

TargetMitogen-activated protein kinase kinase kinase 20(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50184495(1-methyl-5-[2-(6-methyl-pyridin-2-yl)-5,6-dihydro-...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of MLK7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50184495(1-methyl-5-[2-(6-methyl-pyridin-2-yl)-5,6-dihydro-...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of recombinant human TGFbeta R2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50184495(1-methyl-5-[2-(6-methyl-pyridin-2-yl)-5,6-dihydro-...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of recombinant human TGFbeta R1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed