BDBM50184596 (2S,3aS,6aS)-2-methyl-1-(4-(trifluoromethyl)pyrimidin-2-yl)-octahydropyrrolo[3,4-b]pyrrole::CHEMBL210215

SMILES C[C@H]1C[C@H]2CNC[C@H]2N1c1nccc(n1)C(F)(F)F

InChI Key InChIKey=BHZWUADTFGRRTH-XHNCKOQMSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50184596   

Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184596((2S,3aS,6aS)-2-methyl-1-(4-(trifluoromethyl)pyrimi...)
Affinity DataEC50:  151nMAssay Description:Induction of 5HT2B receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184596((2S,3aS,6aS)-2-methyl-1-(4-(trifluoromethyl)pyrimi...)
Affinity DataEC50:  22nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184596((2S,3aS,6aS)-2-methyl-1-(4-(trifluoromethyl)pyrimi...)
Affinity DataEC50:  40nMAssay Description:Induction of 5HT2A receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed