BDBM50185337 5-[3-(3,5-difluoropyridin-2-yl)-4-fluorophenyl]-3-(2-fluorophenyl)pyridazine::CHEMBL206818

SMILES Fc1cnc(c(F)c1)-c1cc(ccc1F)-c1cnnc(c1)-c1ccccc1F

InChI Key InChIKey=CMRJVDJLBFKXKL-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185337   

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185337(5-[3-(3,5-difluoropyridin-2-yl)-4-fluorophenyl]-3-...)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]Ro15-1788 from recombinant human GABA-Aalpha5 receptor plus beta3gamma2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185337(5-[3-(3,5-difluoropyridin-2-yl)-4-fluorophenyl]-3-...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]Ro15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed