BDBM50185751 CHEMBL1602143

SMILES COc1ccc2nc(Nc3nc(O)cc(CSc4nnnn4-c4ccccc4)n3)nc(C)c2c1

InChI Key InChIKey=WPETYAZUCHPYIM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185751   

TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
College Of Chemical And Environmental Engineering

Curated by ChEMBL
LigandPNGBDBM50185751(CHEMBL1602143)
Affinity DataIC50:  2.26E+4nMAssay Description:Inhibition of PRC2 EZH2 sub unit (unknown origin) assessed as inhibition of SAM-mediated methyl transfer process preincubated for 15 mins followed by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed