BDBM50186012 CHEMBL378241::methyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

SMILES COC(=O)C1C(NC(=O)N=C1C)c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=OGPPHNSYTHFUKH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186012   

TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50186012(CHEMBL378241 | methyl 6-methyl-4-(4-nitrophenyl)-2...)
Affinity DataIC50:  4.91E+4nMAssay Description:Inhibition of bovine liver beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by p-nitrophenyl-beta-D-glucuroni...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLong-chain fatty acid transport protein 4(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186012(CHEMBL378241 | methyl 6-methyl-4-(4-nitrophenyl)-2...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human FATP4-mediated 12-BODIPY-lauric acid uptake in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed