BDBM50186430 CHEMBL377184::US8618147, 15::cyclohexylmethyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetate

SMILES Oc1ccc(cc1)C1=NOC(CC(=O)OCC2CCCCC2)C1

InChI Key InChIKey=UFFFPSXGPYDVQV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186430   

TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50186430(CHEMBL377184 | US8618147, 15 | cyclohexylmethyl 2-...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Mus musculus (Mouse))
The Feinstein Institute For Medical Research

US Patent
LigandPNGBDBM50186430(CHEMBL377184 | US8618147, 15 | cyclohexylmethyl 2-...)
Affinity DataIC50:  5.00E+3nMpH: 7.2 T: 2°CAssay Description:MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...More data for this Ligand-Target Pair
In DepthDetails US Patent