BDBM50186706 CHEMBL438612::Cbz-Ile-t-ButylGln-Ala-LeuVSMe

SMILES CC[C@H](C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CCC(=O)NC(C)(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C=CS(C)(=O)=O

InChI Key InChIKey=YIFPZVMURBGBNU-SJPHNPNMSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50186706   

TargetCathepsin S(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186706(CHEMBL438612 | Cbz-Ile-t-ButylGln-Ala-LeuVSMe)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186706(CHEMBL438612 | Cbz-Ile-t-ButylGln-Ala-LeuVSMe)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of post glutamyl peptide hydrolase-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186706(CHEMBL438612 | Cbz-Ile-t-ButylGln-Ala-LeuVSMe)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186706(CHEMBL438612 | Cbz-Ile-t-ButylGln-Ala-LeuVSMe)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of trypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186706(CHEMBL438612 | Cbz-Ile-t-ButylGln-Ala-LeuVSMe)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed