BDBM50187275 (2R,5S)-1-(2-(1-(methoxymethyl)cyclopentylamino)acetyl)pyrrolidine-2,5-dicarbonitrile::CHEMBL379086

SMILES COCC1(CCCC1)NCC(=O)N1[C@@H](CC[C@@H]1C#N)C#N

InChI Key InChIKey=WNRUJDDJBYVIPF-BETUJISGSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50187275   

TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50187275((2R,5S)-1-(2-(1-(methoxymethyl)cyclopentylamino)ac...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50187275((2R,5S)-1-(2-(1-(methoxymethyl)cyclopentylamino)ac...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of DPP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXaa-Pro aminopeptidase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50187275((2R,5S)-1-(2-(1-(methoxymethyl)cyclopentylamino)ac...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of APPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50187275((2R,5S)-1-(2-(1-(methoxymethyl)cyclopentylamino)ac...)
Affinity DataIC50:  84nMAssay Description:Inhibition of human recombinant DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50187275((2R,5S)-1-(2-(1-(methoxymethyl)cyclopentylamino)ac...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50187275((2R,5S)-1-(2-(1-(methoxymethyl)cyclopentylamino)ac...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of DPP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50187275((2R,5S)-1-(2-(1-(methoxymethyl)cyclopentylamino)ac...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed