BDBM50187643 CHEMBL383200::N-(1,3-diphenyl-1H-pyrazol-4-yl)benzamide

SMILES O=C(Nc1cn(nc1-c1ccccc1)-c1ccccc1)c1ccccc1

InChI Key InChIKey=UUVRLWUZZUEUAS-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187643   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50187643(CHEMBL383200 | N-(1,3-diphenyl-1H-pyrazol-4-yl)ben...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]methoxyPEPy from rat mGluR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50187643(CHEMBL383200 | N-(1,3-diphenyl-1H-pyrazol-4-yl)ben...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at mGluR5 assessed as potentiation of glutamate-induced calcium flux in rat astrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed