BDBM50187646 CHEMBL208157::N-(cyclopentylmethyl)carboxyl-1,3-diphenyl-5-amino-1Hpyrazole

SMILES O=C(CC1CCCC1)Nc1cc(nn1-c1ccccc1)-c1ccccc1

InChI Key InChIKey=KVSDNJIDNJOZRL-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187646   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50187646(CHEMBL208157 | N-(cyclopentylmethyl)carboxyl-1,3-d...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]methoxyPEPy from rat mGluR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50187646(CHEMBL208157 | N-(cyclopentylmethyl)carboxyl-1,3-d...)
Affinity DataEC50:  350nMAssay Description:Activity at mGluR5 assessed as potentiation of glutamate-induced calcium flux in rat astrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed