BDBM50187690 CHEMBL3827088

SMILES Fc1ccc(Cc2ncnc3CCN(Cc23)C(=O)CCc2nc3ccccc3s2)cc1

InChI Key InChIKey=JGNVAVQZDSOAGO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50187690   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50187690(CHEMBL3827088)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human recombinant ATX using FS3 as substrate incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50187690(CHEMBL3827088)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human ATXMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50187690(CHEMBL3827088)
Affinity DataIC50:  29nMAssay Description:Inhibition of human ATX using FS-3 as substrate measured after 30 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50187690(CHEMBL3827088)
Affinity DataIC50:  10nMAssay Description:Inhibition of glycosylated human ATX using FS-3 as substrate preincubated for 45 mins under shaking condition followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed