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BDBM50187700 CHEMBL3828042

SMILES: Nc1nc(O)c2ncn(C[C@@H]3N[C@H](CO)[C@@H](O)[C@H]3O)c2n1

InChI Key: InChIKey=JKJZEOAROIEHPY-UGSJSWHKSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187700   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine-adenosine-guanosine-nucleoside hydrolase


(Trypanosoma brucei brucei)
BDBM50187700
PNG
(CHEMBL3828042)
Show SMILES Nc1nc(O)c2ncn(C[C@@H]3N[C@H](CO)[C@@H](O)[C@H]3O)c2n1
Show InChI InChI=1S/C11H16N6O4/c12-11-15-9-6(10(21)16-11)13-3-17(9)1-4-7(19)8(20)5(2-18)14-4/h3-5,7-8,14,18-20H,1-2H2,(H3,12,15,16,21)/t4-,5+,7-,8+/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.60E+3n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma brucei brucei inosine-adenosine-guanosine nucleoside hydrolase expressed in Escherichia coli


Eur J Med Chem 118: 121-42 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.034
BindingDB Entry DOI: 10.7270/Q2ZP482X
More data for this
Ligand-Target Pair
Inosine-uridine preferring nucleoside hydrolase


(Crithidia fasciculata)
BDBM50187700
PNG
(CHEMBL3828042)
Show SMILES Nc1nc(O)c2ncn(C[C@@H]3N[C@H](CO)[C@@H](O)[C@H]3O)c2n1
Show InChI InChI=1S/C11H16N6O4/c12-11-15-9-6(10(21)16-11)13-3-17(9)1-4-7(19)8(20)5(2-18)14-4/h3-5,7-8,14,18-20H,1-2H2,(H3,12,15,16,21)/t4-,5+,7-,8+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
5.40E+3n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Inhibition of Crithidia fasciculata inosine-uridine nucleoside hydrolase expressed in Escherichia coli using p-nitrophenyl beta-D-ribofuranoside as s...


Eur J Med Chem 118: 121-42 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.034
BindingDB Entry DOI: 10.7270/Q2ZP482X
More data for this
Ligand-Target Pair