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BDBM50187702 CHEMBL3828258

SMILES: Nc1ncnc2n(C[C@@H]3N[C@H](CO)[C@@H](O)[C@H]3O)cnc12

InChI Key: InChIKey=SPZGUHBBLQAPQA-JWIUVKOKSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187702   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine-adenosine-guanosine-nucleoside hydrolase


(Trypanosoma brucei brucei)
BDBM50187702
PNG
(CHEMBL3828258)
Show SMILES Nc1ncnc2n(C[C@@H]3N[C@H](CO)[C@@H](O)[C@H]3O)cnc12
Show InChI InChI=1S/C11H16N6O3/c12-10-7-11(14-3-13-10)17(4-15-7)1-5-8(19)9(20)6(2-18)16-5/h3-6,8-9,16,18-20H,1-2H2,(H2,12,13,14)/t5-,6+,8-,9+/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.60E+3n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma brucei brucei inosine-adenosine-guanosine nucleoside hydrolase expressed in Escherichia coli


Eur J Med Chem 118: 121-42 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.034
BindingDB Entry DOI: 10.7270/Q2ZP482X
More data for this
Ligand-Target Pair
Inosine-uridine preferring nucleoside hydrolase


(Crithidia fasciculata)
BDBM50187702
PNG
(CHEMBL3828258)
Show SMILES Nc1ncnc2n(C[C@@H]3N[C@H](CO)[C@@H](O)[C@H]3O)cnc12
Show InChI InChI=1S/C11H16N6O3/c12-10-7-11(14-3-13-10)17(4-15-7)1-5-8(19)9(20)6(2-18)16-5/h3-6,8-9,16,18-20H,1-2H2,(H2,12,13,14)/t5-,6+,8-,9+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
5.40E+3n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Inhibition of Crithidia fasciculata inosine-uridine nucleoside hydrolase expressed in Escherichia coli using p-nitrophenyl beta-D-ribofuranoside as s...


Eur J Med Chem 118: 121-42 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.034
BindingDB Entry DOI: 10.7270/Q2ZP482X
More data for this
Ligand-Target Pair