BDBM50188002 1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phenyl)-3-(3-chlorophenyl)urea::CHEMBL379372

SMILES Nc1ncnc2snc(-c3ccc(NC(=O)Nc4cccc(Cl)c4)cc3)c12

InChI Key InChIKey=WPPDVRZORMAVOK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50188002   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188002(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  50nMAssay Description:Inhibition of KDR by cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188002(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  19nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed