BDBM50188245 CHEMBL3827329

SMILES COc1cccc2c1nc([nH]c2=O)-c1ccc(C)cc1

InChI Key InChIKey=JKCKQJATUNERKN-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50188245   

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50188245(CHEMBL3827329)
Affinity DataIC50:  153nMAssay Description:Inhibition of TNKS-1 (unknown origin) using histone as substrate incubated for 30 mins by colorimetric assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50188245(CHEMBL3827329)
Affinity DataIC50:  167nMAssay Description:Inhibition of N-terminal GST-tagged human TNKS-2 (849 to 1166 residues) expressed in in insect sf21 cells preincubated for 2 hrs followed by substrat...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50188245(CHEMBL3827329)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of PARP-1 (unknown origin) using histone as substrate incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed