BDBM50188368 4-(4-fluoro-phenyl)-8-(2-hydroxy-2-phenyl-cyclohexyl)-2,8-diaza-spiro[4.5]decan-1-one::CHEMBL378253

SMILES OC1(CCCCC1N1CCC2(CC1)C(CNC2=O)c1ccc(F)cc1)c1ccccc1

InChI Key InChIKey=IGMRUXJGIQSJAC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188368   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188368(4-(4-fluoro-phenyl)-8-(2-hydroxy-2-phenyl-cyclohex...)
Affinity DataIC50: >2.40E+7nMAssay Description:Inhibition of hERG potassium channel expressed in CHO cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed