BDBM50189008 (S)-2-((S)-4-((R)-2-amino-3-(4-fluorophenyl)propanoyl)-3-(2-guanidinoethyl)-2-oxopiperazin-1-yl)-N-methyl-3-(naphthalen-2-yl)propanamide::(S)-2-[(S)-4-[(R)-2-Amino-3-(4-fluoro-phenyl)-propionyl]-3-(2-guanidino-ethyl)-2-oxo-piperazin-1-yl]-N-methyl-3-naphthalen-2-yl-propionamide::CHEMBL213566

SMILES [#6]-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc2ccccc2c1)-[#7]-1-[#6]-[#6]-[#7](-[#6@@H](-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6]-1=O)-[#6](=O)-[#6@H](-[#7])-[#6]-c1ccc(F)cc1

InChI Key InChIKey=XAHOMYQYMFNUJP-ZNZIZOMTSA-N

Data  6 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50189008   

TargetMelanocortin receptor 4(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189008((S)-2-((S)-4-((R)-2-amino-3-(4-fluorophenyl)propan...)
Affinity DataKi:  11nMAssay Description:Binding affinity to human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189008((S)-2-((S)-4-((R)-2-amino-3-(4-fluorophenyl)propan...)
Affinity DataKi:  11nMAssay Description:Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189008((S)-2-((S)-4-((R)-2-amino-3-(4-fluorophenyl)propan...)
Affinity DataKi:  470nMAssay Description:Binding affinity to human MC3RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189008((S)-2-((S)-4-((R)-2-amino-3-(4-fluorophenyl)propan...)
Affinity DataKi:  470nMAssay Description:Displacement of europium-labeled NDP-alpha-MSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189008((S)-2-((S)-4-((R)-2-amino-3-(4-fluorophenyl)propan...)
Affinity DataKi:  1.12E+3nMAssay Description:Binding affinity to human MC1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189008((S)-2-((S)-4-((R)-2-amino-3-(4-fluorophenyl)propan...)
Affinity DataKi:  1.12E+3nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as effect on CRE-driven luminescence by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189008((S)-2-((S)-4-((R)-2-amino-3-(4-fluorophenyl)propan...)
Affinity DataEC50:  2.20nMAssay Description:Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189008((S)-2-((S)-4-((R)-2-amino-3-(4-fluorophenyl)propan...)
Affinity DataEC50:  2.20nMAssay Description:Agonist activity at human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189008((S)-2-((S)-4-((R)-2-amino-3-(4-fluorophenyl)propan...)
Affinity DataEC50:  84nMAssay Description:Agonist activity at human MC3RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189008((S)-2-((S)-4-((R)-2-amino-3-(4-fluorophenyl)propan...)
Affinity DataEC50:  353nMAssay Description:Agonist activity at human MC1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed