BDBM50189108 CHEMBL380247::GW574783B::N-(4-(benzyloxy)-3-chlorophenyl)-6-(5-((2-(methylsulfonyl)ethylamino)methyl)furan-2-yl)quinazolin-4-amine

SMILES CS(=O)(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4ccccc4)c(Cl)c3)c2c1

InChI Key InChIKey=HTIFVTQSFKUCDX-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50189108   

Target2''-aminoglycoside nucleotidyltransferase(Klebsiella pneumoniae)
Mcmaster University

LigandPNGBDBM50189108(CHEMBL380247 | GW574783B | N-(4-(benzyloxy)-3-chlo...)
Affinity DataKi:  6.00E+4nMAssay Description:In vitro ANT(2")-Ia pyrophosphatase assays were performed as described previously (Cox et al., 2015; Hirsch et al., 2014), with minor modifications. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50189108(CHEMBL380247 | GW574783B | N-(4-(benzyloxy)-3-chlo...)
Affinity DataIC50:  22nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50189108(CHEMBL380247 | GW574783B | N-(4-(benzyloxy)-3-chlo...)
Affinity DataIC50:  18nMAssay Description:Inhibition of ErbB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed