BDBM50189126 CHEMBL214487::N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-(5-((2-(isopropylsulfonyl)ethylamino)methyl)furan-2-yl)quinazolin-4-amine

SMILES CC(C)S(=O)(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1

InChI Key InChIKey=IRPQLCLTIKGBTQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50189126   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50189126(CHEMBL214487 | N-(4-(3-fluorobenzyloxy)-3-chloroph...)
Affinity DataIC50:  24nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50189126(CHEMBL214487 | N-(4-(3-fluorobenzyloxy)-3-chloroph...)
Affinity DataIC50:  18nMAssay Description:Inhibition of ErbB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed