BDBM50189305 CHEMBL3828410

SMILES NC(=N)c1ccc(NC(=O)C(=O)Nc2ccc(cc2)C(N)=N)cc1

InChI Key InChIKey=DOQCDEYHJCYWQO-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50189305   

TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50189305(CHEMBL3828410)
Affinity DataKi:  492nMAssay Description:Inhibition of human matriptase using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50189305(CHEMBL3828410)
Affinity DataKi:  1.42E+3nMAssay Description:Inhibition of human trypsin using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransmembrane protease serine 6(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50189305(CHEMBL3828410)
Affinity DataKi:  6.23E+3nMAssay Description:Inhibition of human matriptase-2 transfected in HEK cells using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50189305(CHEMBL3828410)
Affinity DataKi:  1.58E+4nMAssay Description:Inhibition of human thrombin using Cbz-Gly-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Bos taurus)
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50189305(CHEMBL3828410)
Affinity DataKi:  5.23E+4nMAssay Description:Inhibition of bovine factor 10a using Boc-Ile-Glu-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed