BDBM50189617 (3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbonyl)-1,4'-bipiperidine::(3R)-1'-(anthracen-9-ylcarbonyl)-3-(morpholin-4-ylcarbonyl)-1,4'-bipiperidine::CHEMBL208943::{(3R)-1'-(anthracen-9-ylcarbonyl)[1,4'-bipiperidin]-3-yl}(morpholin-4-yl)methanone

SMILES O=C([C@@H]1CCCN(C1)C1CCN(CC1)C(=O)c1c2ccccc2cc2ccccc12)N1CCOCC1

InChI Key InChIKey=LDQKDRLEMKIYMC-XMMPIXPASA-N

Data  20 IC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50189617   

TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human recombinant ACC2More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  61nMAssay Description:Inhibitory activity against rat ACC2More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Torrent Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  55nMAssay Description:Inhibition of rat acetyl-CoA carboxylase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase(Rattus norvegicus (Rat))
Torrent Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  55nMAssay Description:Inhibition of rat acetyl-CoA carboxylase 2More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  194nMAssay Description:Inhibition of human recombinant ACC2More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Torrent Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  53nMAssay Description:Inhibition of rat ACC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase(Rattus norvegicus (Rat))
Torrent Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  61nMAssay Description:Inhibition of rat ACC2More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  456nMAssay Description:Inhibition of human recombinant ACC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Torrent Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  92nMAssay Description:Inhibition of rat liver ACC1 after 7 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Torrent Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  590nMAssay Description:Inhibition of N-terminal His-tagged rat recombinant ACC1 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  910nMAssay Description:Inhibition of N-terminal His-tagged human recombinant ACC1 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  70nMAssay Description:Inhibition of N-terminal His-tagged human recombinant ACC2 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase(Rattus norvegicus (Rat))
Torrent Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  170nMAssay Description:Inhibition of ACC2 in obese Zucker rat assessed as reduction in hepatic malonyl-coA level preincubated for 15 mins measured after 1.5 hrs using Malac...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Torrent Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  230nMAssay Description:Inhibition of obese Zucker rat ACC1 assessed as reduction in hepatic malonyl-coA level preincubated for 15 mins measured after 1.5 hrs using Malachit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  550nMAssay Description:Inhibition of human ACC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  34nMAssay Description:Inhibition of human ACC2More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  410nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human recombinant ACC2 expressed in baculovirus/sf9 systemMore data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Torrent Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  53nMAssay Description:Inhibitory activity against rat ACC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50189617((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...)
Affinity DataIC50:  410nMAssay Description:Inhibition of human recombinant ACC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed