BDBM50189649 CHEMBL212260::N-{1-(1H-benzoimidazol-2-yl)-2-[4-(1,1,3-trioxo-1lambda*6*-isothiazolidin-5-yl)-phenyl]-ethyl}-2-cyano-benzenesulfonamide

SMILES O=C1CC(c2ccc(CC(NS(=O)(=O)c3ccccc3C#N)c3nc4ccccc4[nH]3)cc2)S(=O)(=O)N1

InChI Key InChIKey=MPZYBWIJDLDGEE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50189649   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50189649(CHEMBL212260 | N-{1-(1H-benzoimidazol-2-yl)-2-[4-(...)
Affinity DataIC50:  45nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed