BDBM50189770 5-[5-(2-chlorophenyl)furan-2-ylmethylene]thiazolidine-2,4-dione::CHEMBL211113

SMILES OC1=NC(=O)C(S1)=Cc1ccc(o1)-c1ccccc1Cl

InChI Key InChIKey=UKOAKDJZVZQHAH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50189770   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189770(5-[5-(2-chlorophenyl)furan-2-ylmethylene]thiazolid...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189770(5-[5-(2-chlorophenyl)furan-2-ylmethylene]thiazolid...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of PI3Kgamma (unknown origin) assessed as decrease in fluorescence intensity using phosphorylated substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed